Endometriosis in Adolescents: Diagnostics, Clinical and Laparoscopic Features

Khashchenko, E.P.; Uvarova, E.V.; Fatkhudinov, T.K.; Chuprynin, V.D.; Asaturova, A.V.; Kulabukhova, E.A.; Vysokikh, M.Y.; Allakhverdieva, E.Z.; Alekseeva, M.N.; Adamyan, L.V.; Sukhikh, G.T.

Авторы: Khashchenko Elena P., Uvarova Elena V., Fatkhudinov Timur Kh, Chuprynin Vladimir D., Asaturova Aleksandra V., Kulabukhova Elena A., Vysokikh Mikhail Yu, Allakhverdieva Elvina Z., Alekseeva Maria N., Adamyan Leila V., Sukhikh Gennady T.
Журнал: JOURNAL OF CLINICAL MEDICINE
Том: 12
Номер: 4
Год издания: 2023
Номер статьи: 1678
DOI: 10.3390/jcm12041678
Аннотация: The early diagnosis of endometriosis in adolescents is not developed. Objective: We aim to conduct clinical, imaging, laparoscopic and histological analyses of peritoneal endometriosis (PE) in adolescents in order to improve early diagnosis. Methods: In total, 134 girls (from menarche to 17 years old) were included in a case–control study: 90 with laparoscopically (LS) confirmed PE, 44 healthy controls underwent full examination and LS was analyzed in the PE group. Results: Patients with PE were characterized with heredity for endometriosis, persistent dysmenorrhea, decreased daily activity, gastrointestinal symptoms, higher LH, estradiol, prolactin and Ca-125 (<0.05 for each). Ultrasound detected PE in 3.3% and MRI in 78.9%. The most essential MRI signs are as follows: hypointense foci, the heterogeneity of the pelvic tissue (paraovarian, parametrial and rectouterine pouch) and sacro-uterine ligaments lesions (<0.05 for each). Adolescents with PE mostly exhibit initial rASRM stages. Red implants correlated with the rASRM score, and sheer implants correlated with pain (VAS score) (<0.05). In 32.2%, foci consisted of fibrous, adipose and muscle tissue; black lesions were more likely to be histologically verified (0.001). Conclusion: Adolescents exhibit mostly initial PE stages, which are associated with greater pain. Persistent dysmenorrhea and detected MRI parameters predict the laparoscopic confirmation of initial PE in adolescents in 84.3% (OR 15.4; <0.01), justifying the early surgical diagnostics and shortening the time delay and suffering of the young patients.
Добавил в систему: Высоких Михаил Юрьевич

	ИСТИНА	Войти в систему Регистрация
	Интеллектуальная Система Тематического Исследования НАукометрических данных
	Главная Поиск Статистика О проекте Помощь

ИСТИНА

Интеллектуальная Система Тематического Исследования НАукометрических данных

Endometriosis in Adolescents: Diagnostics, Clinical and Laparoscopic Featuresстатья Исследовательская статья

Прикрепленные файлы