Physico-mechanical properties of Mg and Ag doped hydroxyapatite/chitosan biocompositesстатья

Информация о цитировании статьи получена из Scopus, Web of Science
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Дата последнего поиска статьи во внешних источниках: 19 декабря 2017 г.

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[1] Physico-mechanical properties of mg and ag doped hydroxyapatite/chitosan biocomposites / S. F. Mansour, S. I. El-dek, S. V. Dorozhkin, M. K. Ahmed // New Journal of Chemistry. — 2017. — Vol. 41, no. 22. — P. 13773–13783. Nano-hydroxyapatite/chitosan (nano-HAP/CS) composites with high compressive strength were synthesized using microwave assisted co-precipitation. Co-Doping using Mg2+ and Ag+ was carried out simultaneously in HAP resulting in the formula: [MgxAgyCa(10-x-y)(PO4)6(OH)2; 0 < (x + y) < 1]. The samples were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HRTEM). The results illustrated that the shape, size and crystallinity index of the prepared nano-HAP crystals were similar to those of natural bone. Doping by Ag+ was performed to produce an anti-bacterial effect, while Mg2+ dopant appeared to be a crucial factor in improving the mechanical properties. Furthermore, mechanical testing exhibited that the maximum compressive strength of the new composite was 15 MPa. The multifunctional non-sintered materials showed promising results in drug loaded bioceramics with improved mechanical features in bone tissue engineering. [ DOI ]

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