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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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Ultrastructural study and X-ray microanalysis of apoptotic lymphoma cells U-937статья
- Авторы: Snigirevskaya E.S., Moshkov A.V., Komissarchik Ya Yu
- Журнал: Biochemistry & Molecular Biology Journal
- Том: 3
- Номер: 3
- Год издания: 2017
- Издательство: iMedPub LTD
- Местоположение издательства: London, UK
- Первая страница: 1
- Последняя страница: 2
- DOI: 10.21767/2471-8084.100041
- Аннотация: the aggregates observed in U-937 cell line allowed identification of three types of nuclear particles dominating in these aggregates: 1) interchromatin granules of 10 x 40 nm, 2) proteasomes of 10-15 × 30 nm, 3) long perichromatin fibers. Pperichromatin fibers on sections contrasted with uranyl-acetate were seen as elongated electron dense particles 12-13 nm thick with a periodic structure with a period of 10 nm and formed by 4 nm thick helical threads PFs, suggesting presence RNA- and RNP-containing structures. We demonstrated translocation of PFs from the nucleus to cytoplasm via nuclear pores. By application of X-ray microanalysis, we were able to detect changes in the intracellular contents of Na+ and K+ during apoptosis induced by osmotic shock. An increased ratio of intracellular Na+/K+ was detected for majority of the cells entering apoptosis.
- Добавил в систему: Комиссарчик Ян Юдович