Role of mechano-dependent ion channels in pulsational growth of colonial hydroidsтезисы доклада

Дата последнего поиска статьи во внешних источниках: 28 мая 2015 г.

Работа с тезисами доклада


[1] Nikishin D., Kremnyov S. Role of mechano-dependent ion channels in pulsational growth of colonial hydroids // 5th Meeting of the European Society for Evolutionary Developmental Biology . 22-25 July 2014. Viena, Austria. — Program and Abstract Book. — Viena, Austria, 2014. — P. 366–367. Apical growth in all parts of the colonial hydroids occurs as a result of growth pulsations. Pulsational growth of hydroids is an interesting example of cyclic morphogenetic processes. It is well known that the apical morphogenesis hydroids accompanied by changes in the parameters of growth pulsations and possibly determined by these changes. The investigation of the mechanisms underlying the pulsational growth of hydroids has important implications for understanding the evolution of morphogenesis. We investigated the physiological mechanisms of cell movement pulsational growth, in particular the role of mechanosensitive ion channels that process. As object of research we chose the top of the stolons, as the most simple system which is not subject morphogenesis and convenient methodologically. Colonies of Gonothyraea loveni cultivated on glass slides, and growth pulsations recorded and processed automatically by an original computer program written to track the movements of individual cells. Gadolinium ion is used as a blocker of mechanodependent ion channels. Gadolinium significantly slowed the growth of the tips of stolons at a concentration of 50 uM and completely inhibited it at 100 uM. The effect is reversible and is abolished after washing gadolinium. The obtained results indicate the involvement of mechano-dependent ion channels in pulsational growth of colonial hydroids.

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