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Effects of Ionizing Radiation in Cancer Radiotherapyстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Alhaddad Lina, Pustovalova Margarita, Osipov Andreyan N., Leonov Sergey
- Журнал: International Journal of Molecular Sciences
- Год издания: 2025
- Издательство: MDPI
- Местоположение издательства: Basel, Switzerland
- Первая страница: 1
- Последняя страница: 216
- Аннотация: For a long time, it was widely accepted that the biological effects of ionizing radiation such as cell death, DNA damage, and mutagenesis result from the direct ionization of cell structures, particularly DNA, or from indirect damage through reactive oxygen species produced by the radiolysis of water. This “targeted effect” (TE) model has been questioned by numerous observations, in which cells, that were not directly irradiated, exhibited responses similar to those of the directly irradiated cells. Therefore, it is nowadays accepted that the detrimental effects of ionizing radiation are not restricted only to the irradiated cells, but also to non-irradiated adjacent or distant cells
- Добавил в систему: Алхаддад Лина