Osteoconductive bioceramics based on resorbable calcium phosphatesтезисы доклада

Дата последнего поиска статьи во внешних источниках: 27 января 2018 г.

Работа с тезисами доклада

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1. ESB_2017_Kurbatova_775.pdf ESB_2017_Kurbatova_775.pdf 643,0 КБ 5 сентября 2017 [safronova]

[1] Osteoconductive bioceramics based on resorbable calcium phosphates / K. Snezhana, S. Tatiana, E. Pavel et al. // 28th Annual conference of the European Society for Biomaterials (ESB 2017). Book of Abstracts. — Translational activities for exploiting research on Biomaterials. — Megaron Athens International Conference Centre, Athens, Greece, 2017. — P. 775–775. Three research objects were chosen in the framework of this work: calcium polyphosphate Ca(PO3)2 (Ca/P=0,5), calcium pyrophosphate Ca2P2O7 (Ca/P=1) and the mixture of these compounds in the 1:1 ratio (Ca/P=0,75). Powders of amorphous hydrated calcium phosphates with these Ca/P ratios were obtained by means of wet precipitation method using ion exchange from solutions of sodium poly- and pyrophosphates and calcium acetate. Then, dried powders were heat treated under different temperatures. In order to obtain ceramic material using stereolithography, it is necessary to use suspensions containing powder of the demanded phase composition and a light-cured monomer. Three parameters were varied in the study of the suspensions for further stereolithography application: composition of powder (Ca/P=0,5; 0,75; 1), the temperature (500, 700, or 900oC) of preliminary heat treatment of the CPP powder and the content of powder (2–40 vol.%) in the slurry. The samples of macroporous composite materials were printed by means of the stereolithography. The structure with the architecture of gyroid was chosen for stereolithographic printing, since it is one of the most promising models for producing osteoconductive materials. Macroporous ceramic samples were obtained after the heat treatment of these composites. The method of amorphous hydrated calcium phosphates synthesis using ion exchange was elaborated. The properties of the suspensions (viscosity, photosensitivity, and critical energy of polymerization) were explored. It was shown that the variation of the photosensitivity of suspensions by changing the colour of powder could sufficiently improve the resolution of stereolithographic printing. Ceramic materials with high osteoconductive properties were obtained using stereolithographic printing. Created porous ceramics based on calcium poly- and pyrophosphated exhibit good resorbability and osteoconductivity and are suitable for medical applications.

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