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Protection mechanism of Dps protein of bacterial DNA during sublethal heat shockстатья
- Авторы: Tereshkina Ksenia, Victoriya Potokina, Eduard Tereshkina, Kovalenko Vladislav, Krupyanskii Yurii, Loiko Nataliya
- Журнал: Mendeleev Communications
- Том: 35
- Год издания: 2025
- Издательство: Russian Academy of Sciences
- Местоположение издательства: Russian Federation
- Первая страница: 139
- Последняя страница: 141
- Номер статьи: 24/7596
- DOI: 10.71267/mencom.7596
- Аннотация: The mechanism of protective action of the DNA-binding protein Dps from Escherichia coli during sublethal exposure to thermal shock has been deciphered using in vivo experimental methods and in silico molecular modelling methods. The strength of the DNA–Dps complex was shown to increase when the temperature was raised to 55 °C, and to maintain this state after cooling down to 28 °C. It is proved that this favors the survival of bacteria and their acquisition of additional stress resistance.
- Добавил в систему: Терешкина Ксения Борисовна