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The Set of Serine Peptidases of the Tenebrio molitor Beetle: Transcriptomic Analysis on Different Developmental Stagesстатья Исследовательская статья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 26 июня 2024 г.
- Авторы: Zhiganov Nikita I., Vinokurov Konstantin S., Salimgareev Ruslan S., Tereshchenkova Valeriia F., Dunaevsky Yakov E., Belozersky Mikhail A., Elpidina Elena N.
- Журнал: International Journal of Molecular Sciences
- Том: 25
- Номер: 11
- Год издания: 2024
- Издательство: MDPI
- Местоположение издательства: Basel, Switzerland
- Номер статьи: 5743
- DOI: 10.3390/ijms25115743
- Аннотация: Serine peptidases (SPs) of the chymotrypsin S1A subfamily are an extensive group ofenzymes found in all animal organisms, including insects. Here, we provide analysis of SPs in theyellow mealworm Tenebrio molitor transcriptomes and genomes datasets and profile their expressionpatterns at various stages of ontogeny. A total of 269 SPs were identified, including 137 with conservedcatalytic triad residues, while 125 others lacking conservation were proposed as non-active serinepeptidase homologs (SPHs). Seven deduced sequences exhibit a complex domain organization withtwo or three peptidase units (domains), predicted both as active or non-active. The largest groupof 84 SPs and 102 SPHs had no regulatory domains in the propeptide, and the majority of themwere expressed only in the feeding life stages, larvae and adults, presumably playing an importantrole in digestion. The remaining 53 SPs and 23 SPHs had different regulatory domains, showedconstitutive or upregulated expression at eggs or/and pupae stages, participating in regulation ofvarious physiological processes. The majority of polypeptidases were mainly expressed at the pupaland adult stages. The data obtained expand our knowledge on SPs/SPHs and provide the basis forfurther studies of the functions of proteins from the S1A subfamily in T. molitor.
- Добавил в систему: Терещенкова Валерия Феликсовна
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Полный текст | ijms-25-05743-v2.pdf | 6,4 МБ | 24 июня 2024 [ValeriyaSh] |