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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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Comparative lecithin-cholesterol-acyltransferase deficiency in the blood of newborn infants. Comparison of the esterifying activity of neonatal and maternal bloodстатья
- Авторы: Nikiforova A.A., Chistiakova A.M., Matveev I.I., Teriukova N.P., Arkhipov O.P.
- Журнал: Vopr Med Khim (Moskva, Russia (Federation))
- Том: 24
- Номер: 1
- Год издания: 1978
- Первая страница: 87
- Последняя страница: 92
- Аннотация: On the basis of data obtained in studies on the accumulation of cholesterol in erythrocytes of newlorns, the hypothesis is advanced on the deficiency of lecithin-cholesterol-acetyl transferase (LCAT) in the newborn children. A decrease in the rate of the LCAT-reaction was shown in funic blood using the specially developed system "LP-infranatante", the constituents of which were isolated from blood plasma of both newborns and of their mothers by ultracentrifugation at a density 1.21 g/ml and 40.000 rpm. The following factors were considered as possible determinants of the decrease in the rate of cholesterol esterification in blood plasma of newborns: 1) insufficiency in LCAT, 2) alteration in the composition of the substrate lipoproteins (lipoproteins of high density).
- Добавил в систему: Терюкова Наталья Павловна