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Detection and evaluation of different morphological forms of Mycoplasma hominis in human semenстатья
- Авторы: Bragina Elizaveta, Sorokina Tatyana, Chogovadze Avtandil, Shevchenko Yulia, Chernykh Vyacheslav, Barkhatova Olga, Rakovskaya Irina
- Журнал: Asian Journal of Andrology
- Том: 25
- Год издания: 2023
- Издательство: Shanghai Institute of Materia Medica
- Местоположение издательства: China
- Первая страница: 1
- Последняя страница: 6
- DOI: 10.4103/aja202333
- Аннотация: Recently discovered microcolonial forms of Mycoplasma hominis (M. hominis) and their impact on human spermatogenesis arestudied. The spermatozoa of 125 fertile men (sperm donors; from Reprobank [Reproductive Tissue Bank, Moscow, Russia]) and of93 patients with fertility problems (from the Federal State Budgetary Institution “Research Centre for Medical Genetics [RCMG]”,Moscow, Russia) were used. Classical colonies of M. hominis and microcolonies were detected by molecular biological methods, cultureof bacteria, and transmission electron microscopy. The unique structure of microcolonial cells, in which the cytoplasmic cylinder issurrounded by concentric electron-dense and electron-light layers with a periodicity of 12–14 nm, and the ability of microcolonialcells to attach to spermatozoa are shown. In patients with lower sperm quality, microcolonies of M. hominis were detected 2.5 timesmore frequently than classical colonies. The detection of microcolonies in the ejaculate and the frequent isolation of microcoloniesfrom sperm samples of patients with fertility problems suggest that microcolonial cells may be one cause of infertility.
- Добавил в систему: Брагина Елизавета Ефимовна
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Полный текст | detection_and_evaluation_of_different.125.pdf | 2,0 МБ | 25 сентября 2023 [BraginaEe] |