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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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Control of DNA integrity in skeletal muscle under physiological and pathological conditionsстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Bou Saada Y., Dib C., Zaharova V.V., Chernyak B.V., Carnac G., Dokudovskaya S., VASSETZKY Y.S.
- Журнал: Cellular and Molecular Life Sciences
- Год издания: 2017
- Издательство: Birkhauser Verlag
- Местоположение издательства: Switzerland
- DOI: 10.1007/s00018-017-2530-0
- Аннотация: Skeletal muscle is a highly oxygen-consuming tissue that ensures body support and movement, as well as nutrient and temperature regulation. DNA damage induced by reactive oxygen species is present in muscles and tends to accumulate with age. Here we present a summary of data obtained on DNA damage and its implication in muscle homeostasis, myogenic differentiation and neuromuscular disorders. Controlled and transient DNA damage appears to be essential for muscular homeostasis and differentiation while uncontrolled and chronic DNA damage negatively affects muscle health.
- Добавил в систему: Васецкий Егор Сергеевич