Аннотация:Uranium oxide microparticles ingestion is one of the potential sources of internal radiation doses tothe humans at accidental or undesirable releases of radioactive materials. It is important to predictthe obtained dose and possible biological effect of these microparticles by studying uranium oxidestransformations in case of their ingestion or inhalation. Using a combination of methods, a complexexamination of structural changes of uranium oxides in the range from UO2 to U4O9, U3O8 and UO3 aswell as before and after exposure of uranium oxides in simulated biological fluids: gastro-intestinaland lung—was carried out. Oxides were thoroughly characterized by Raman and XAFS spectroscopy.It was determined that the duration of expose has more influence on all oxides transformations. Thegreatest changes occurred in U4O9, that transformed into U4O9-y. UO2.05 and U3O8 structures becamemore ordered and UO3 did not undergo significant transformation.