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The Development of Medical Shampoo with the Plant-Based Substance for the Treatment of Seborrheic Dermatitisстатья
- Авторы: Filatov V.A., Kulyak O.Y., Kalenikova E.I.
- Журнал: Medical Sciences Forum
- Том: 3
- Год издания: 2023
- Издательство: MDPI
- Местоположение издательства: Basel, Switzerland
- Первая страница: 1
- Последняя страница: 6
- Номер статьи: 51
- DOI: 10.3390/ECB2023-14084
- Аннотация: Dermatological diseases of the scalp significantly affect the life quality of people. According to statistical data, seborrheic dermatitis (SD) is the most common dermatological disease in more than 50% of the population all over the world. There are many possible causes of SD including sebum accumulation, less frequent shampooing, and sensitivity to hair care products. Maintaining personal cleanliness and reducing unwanted effects on scalp can be achieved by application of special shampoo. Most commercial antidandruff shampoos employ synthetic substances as active ingredients, but their regular use changes a biodiversity of scalp microflora and determines subsequent antimicrobial resistance. Therefore, the aim of study was the development of medical shampoo with plant-based pharmaceutical substance for treatment of SD. The inhibitory activity against S. epidermidis, S. aureus, C. albicans of the plant-based substance based on M. alternifolia essential oil, 1,8-cineol (eucalyptol) and α-(-)-bisabolol and shampoo containing the substance were investigated by micro-broth dilution and broth dilution method, respectively. The medical shampoo with 0.75% substance possessed high antibacterial activity against S. epidermidis and S. aureus with log CFU>1.0. Interestingly, the antifungal activity against C. albicans (model of Malassezia spp.) was compatible to that of ketoconazole, climbazole and piroctone olamine. Shampoo with developed combination of surfactants as lauryl glucoside, sodium coco-sulfate, coco-glucoside and cocamidopropyl betaine had the best formulation in terms of microbiology and pH-stability, density foam characteristics, hair smoothness, soothing and scalp cleansing. Therefore, this medical shampoo with natural origin ingredients was suggested for use in treatment of SD and dandruff. sciforum-067826
- Добавил в систему: Каленикова Елена Игоревна
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 2. | Полный текст | Med_Sci_Foruv_2023_Filatov_msf-21-00051.pdf | 237,2 КБ | 7 августа 2023 [Elena_Kalenikova] |