Аннотация:Bacteria use diverse regulatory RNAs to coordinate their physiological processes. Although their spectrum differs from that of higher organisms, the basic principles of action are similar, and many types of non-coding RNAs are present in both kingdoms. Being multifunctional in their ability to interact with various proteins and nucleic acids, small RNAs (sRNAs) encoded by their own genes, as well as fragments of tRNAs, rRNAs, 3′-UTRs, and antisense RNAs, have recently gained increasing attention due to their potential ability to act as signaling molecules establishing interkingdom communications between hosts and microbes. Thus, the goal of the Research Topic was to collect cutting-edge studies exploring biogenesis and RNA-mediated regulatory pathways operating inside bacterial cells and beyond their boundaries.