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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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WEBINO Syndrome in a Patient with Progressive Supranuclear Palsy: Case Report and Literature Reviewстатья
- Авторы: Sherstyuk E.E., Belyakova-Bodina A.I., Nuzhnyi E.P., Shpilyukova Yu A., Broutian A.G.
- Журнал: Human Physiology
- Том: 48
- Номер: 8
- Год издания: 2022
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 912
- Последняя страница: 918
- DOI: 10.1134/s0362119722080126
- Аннотация: A clinical case of a patient with progressive supranuclear palsy (PSP) and wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) syndrome identified using video-oculography and ophthalmological examination is presented. WEBINO syndrome is a combination of bilateral internuclear ophthalmoplegia and exodeviation. Few cases of such oculomotor disorder in PSP patients have been earlier described. However, a closer look at the pathogenesis of co-existing internuclear ophthalmoplegia and strabismus reveals its common features with the origins of typical oculomotor disorders seen in PSP. Therefore, this horizontal eye movement impairment might be not so uncommon in PSP patients. Diplopia as one of the subjective manifestations of WEBINO is a treatable phenomenon. Its management is capable of improving the gait function, severely affected in PSP. Practical recommendations are given for neurologists to improve the detection of horizontal gaze dysfunction in PSP and the role of instrumental methods of examination is explained. Awareness of clinical practitioners of WEBINO syndrome will not only elevate the quality of help for PSP patients, but also expand the understanding of pathogenesis of oculomotor abnormalities in this type of atypical parkinsonism.
- Добавил в систему: Шпилюкова Юлия Александровна