SINGLE SKIN EXPOSURE TO VISIBLE POLARIZED LIGHT INDUCES RAPID MODIFICATION OF ENTIRE CIRCULATING BLOOD. 2. APPEARANCE OF SOLUBLE FACTORS RESTORING PROLIFERATION AND CHROMOSOME STRUCTURE IN X-DAMAGED LYMPHOCYTESстатья

Информация о цитировании статьи получена из Scopus, Web of Science
Дата последнего поиска статьи во внешних источниках: 11 апреля 2017 г.

Работа с статьей


[1] Single skin exposure to visible polarized light induces rapid modification of entire circulating blood. 2. appearance of soluble factors restoring proliferation and chromosome structure in x-damaged lymphocytes / K. A. Samoilova, O. I. Zubanova, S. A. Snopov et al. // PROCEEDINGS OF SPIE - THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING. — 1999. — P. 26–33. Exposure of a small skin area (400 cm2) of volunteers to visible incoherent polarized (VIP) light (400 - 2000 nm) in therapeutic doses is accompanied by rapid appearance in the circulating blood of soluble factors able to restore proliferation of X-ray-damaged autologous lymphocytes and to decrease frequency of chromosome breaks. The appearance of a such activity in blood can also be induced without skin irradiation, by in vitro modeling of mixing in the circulation of a small amount of transcutaneously VIP- irradiated blood with the intact blood (one volume of the directly VIP-irradiated blood was added to 10 volumes of the intact blood). Hence, the blood (not the skin) is a major source of the active factors. The data obtained indicate a possibility of release of them from photomodified platelets; moreover, the activity restoring chromosome structure in X- damaged cells has been found in the platelet-derived growth factor and epidermal growth factor (which are known to be associated with platelets) when they were added to physiological concentrations to the culture medium. We assume that activation of cell proliferation based on the effective repair of DNA damaged in situ by endogenous and exogenous factors could be one of the mechanisms of photostimulation of wound healing. © (1998) COPYRIGHT SPIE–The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only. [ DOI ]

Публикация в формате сохранить в файл сохранить в файл сохранить в файл сохранить в файл сохранить в файл сохранить в файл скрыть