Laser speckle contrast imaging for intraoperative monitoring of cerebral blood flow

Stavtsev, D.D.; Konovalov, A.N.; Blinova, E.V.; Piavchenko, G.A.; Golodnev, G.E.; Zalogin, S.D.; Gorina, A.V.; Lapin, K.N.; Vagner, S.A.; Grebenev, F.V.; Meglinski, I.V.; Gerasimenko, A.Y.; Telyshev, D.V.; Kuznetsov, S.L.

Авторы: Stavtsev D.D., Konovalov A.N., Blinova E.V., Piavchenko G.A., Golodnev G.E., Zalogin S.D., Gorina A.V., Lapin K.N., Vagner S.A., Grebenev F.V., Meglinski I.V., Gerasimenko A.Yu, Telyshev D.V., Kuznetsov S.L.
Журнал: Bulletin of the Russian Academy of Sciences: Physics
Том: 86
Номер: 13
Год издания: 2022
Издательство: Allerton Press Inc.
Местоположение издательства: United States
Первая страница: 229
Последняя страница: 233
DOI: 10.3103/S1062873822700733
Аннотация: During neurosurgical operations, blood low monitoring is of great importance for the surgeon to make informed decisions. This is particularly important for neurovascular interventions such as clipping cerebral vessel aneurysms, bypass and avm surgery . Fluorescence angiography and Doppler sonography are standard bloodflow control methods, which have a number of limitations. Laser speckle contrast imaging (LSCI) can provide non-invasive blood flow control throughout the operation without the introduction of special contrast agents. This method is based on the irradiation of living tissues with coherent laser radiation, which is backscattered and forms a random interference speckle pattern. This speckle pattern is recorded by a digital camera and statistically processed to determine to obtain blood flow images in vessels and the microcirculatory of cerebral cortex and major vessels. A number of studies have demonstrated the use of LSCI for monitoring of cerebral blood flow during neurosurgical interventions. In this work, a prototype LSCI system was developed for use on a rat model with simulated real-time monitoring of blood flow.
Добавил в систему: Коновалов Антон Николаевич

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