Аннотация:The international biomedical community is currently faced with the question of finding the simplest and most accessible type of analysis that helps to diagnose tuberculosis (TB) with maximum reliability even before the onset of clinical manifestations. Tuberculosis causes more deaths than any other pathogen, second only to pneumonia caused by the SARS-2-COVID-19 virus, but most people who are infected carry it without symptoms. In addition, it is important to develop methods to distinguish in the early stages of various forms of the course of tuberculosis infection and to reliably divide patients into appropriate groups (persons with a rapidly progressing infection, a chronic course, latent infection carriers).