Аннотация:Reaction of copper(II) acetate with 5-nitro-2-furoic acid (NO2-Hfur) and N-donor ligands2,2'-bipyridine (bpy) and pyridine (py) has resulted in complexes [Cu(NO2-fur)2(H2O)2]·2H2O (I),[Cu(NO2-fur)2(py)2(H2O)] (II), and binuclear [Cu2(NO2-fur)4(bpy)2]·H2O (III) whose structure was deter-mined by X-ray diffraction study. Cation Cu2+ is in square-planar (I) or square-pyramidal (II, III) environ-ment and has CN(Cu) = 4 (I) or 5 (II, III), respectively. Stability of complexes I–III in solid phase has beendetermined by synchronous thermal analysis, stability in solutions has been studied by electronic absorptionspectroscopy. Compounds I and II are thermally stable (>100°С). The presence of nitro group in the com-plexes causes strong exothermal effects, whose intensity is leveled by donor ligand. The storage of solutionsof the compounds in 5% glucose solution and 0.9% NaCl for 2 days according to UV spectroscopy causes notheir degradation. Biological activity of complexes I–III was studied in vitro toward non-pathogenic strainM. smegmatis (behaves as a model for M. tuberculosis); antimicrobial activity of compound II toward a num-ber of Gram-positive and Gram-negative bacteria has been investigated.
