Ultrasonic Nanomedicine in the Therapy of Oncological Diseases

Авторы: Gopin A.V., Nikolaev A.L., Bozhevolnov V.E., Mazina S.E., Treschalina E.M., Dezhkunov N.V.
Сборник: Proceedings of the International Conference Nanomaterials: Applications and Properties
Том: 2
Год издания: 2013
Первая страница: 04NABM04-1
Последняя страница: 04NABM04-3
Аннотация: In this paper the authors develop the concept of using solid-phase nanoscale inclusions in biological structures, as the concentrators of acoustic energy for ultrasound therapy of oncological diseases. Particular attention is paid to possibility of synthesis of these inclusions directly in the tumor tissue. The validity of the hypothesis of solid-phase sonosensitization has been confirmed in vitro on bacterial cultures. Super-additive effect of combined action of ultrasound and solid-phase sonosensitizer on bacterial cultures was shown. Experimental studies on animals showed that the ultrasound exposure of malignant tumors containing nanoparticles of gold and some complex compounds (e.g. theraphthal) results in a significant therapeutic effect, which is expressed in a considerable inhibition of tumor growth.
Добавил в систему: Гопин Александр Викторович

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