Polypill concept in the treatment of arterial hypertension (review)

Авторы: Tserkovnaya K.M., Kotsur Yu M., Okovityi S.V., Ivkin D.Yu, Kulikov A.N., Flisyuk E.V., Narkevich I.A.
Журнал: Pharmaceutical Chemistry Journal
Том: 56
Номер: 5
Год издания: 2022
Издательство: Kluwer Academic/Plenum Publishers
Местоположение издательства: United States
Первая страница: 577
Последняя страница: 582
DOI: 10.1007/s11094-022-02678-z
Аннотация: This review discusses relevant issues of antihypertensive therapy with fixed-dose combination pills (polypills). Special features of polypills are considered. Their technology classification is given. Evidence is presented that treatment with polypills affecting several risk factors (e.g., antihypertensive, hypolipidemic, antithrombotic) can improve medication adherence; provide effective cure, particularly blood pressure (BP) lowering; and cause fewer adverse events. It is important to note that polypill-based therapy implements a personalized approach in the treatment of hypertension, provides effective and safe BP control, and decreases the level of cardiovascular risk factors.
Добавил в систему: Оковитый Сергей Владимирович

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