Аннотация:The study of circadian rhythms in the human body using temperature measurements is themost informative way to assess the viability of the body’s rhythm-organizing systems. Pathologicalprocesses can affect circadian rhythm dynamics in damaged organs. Severe brain damage that causedthe development of disorders of consciousness (DOC) (strokes, traumatic brain injury) disruptsthe activity of central oscillators, by directly damaging or destroying the periphery links, and thelevel of preservation of circadian rhythms and the dynamics of their recovery can be informativediagnostic criteria for patient’s condition assessment. This study examined 23 patients with DOCby using a non-invasive method for obtaining body and cerebral cortex temperature to comparewith healthy controls. Measurements were made with a 4 h interval for 52 h beginning at 08:00 onday 1 and ending at 08:00 on day 3. The profile of patients with DOC showed complete disruptioncompared to healthy controls with rhythmic patterns. The results indicate that the mechanisms formaintaining brain circadian rhythms are different from general homeostasis regulation of the body.Use of microwave radio thermometry for the identification of rehabilitation potential in patients withDOC is a promising area of investigation.