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Comparison of exposure assessment methods for occupational carcinogens in a multi-centre lung cancer case-control studyстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или ScopusДата последнего поиска статьи во внешних источниках: 4 марта 2022 г.
- Авторы: Peters S., Vermeulen R., Cassidy A., Mannetje A.’., van Tongeren M., Boffetta P., Straif K., Kromhout H., Zaridze D., Szeszenia-Dabrowska N., Rudnai P., Lissowska J., Fabianova E., Mates D., Bencko V., Foretova L., Janout V., Fevotte J., Fletcher T., Brennan P.
- Журнал: Occupational and Environmental Medicine
- Том: 68
- Номер: 2
- Год издания: 2011
- Издательство: BMJ Publishing Group
- Местоположение издательства: United Kingdom
- Первая страница: 148
- Последняя страница: 153
- Аннотация: Retrospective exposure assessment remains a problematic aspect of population-based case-control studies. Different methods have been developed, including case-by-case expert assessment and job-exposure matrices (JEM). The present analyses compare exposure prevalence and risk estimates derived by different exposure assessment methods.\ In the context of a case-control study conducted in seven European countries, exposure was estimated for asbestos, diesel motor emissions (DME) and crystalline silica, using three different assessment methods. First, experts assigned exposures to all reported jobs on a case-by-case basis. Second, a population-specific JEM (PSJEM) was developed using the expert assessments of controls only, and re-applied to all study subjects. Third, an independent general population JEM (GPJEM) was created by occupational exposure experts not involved in the original study, and applied to study subjects. Results from these methods were compared.\ 0.01) between countries for all three agents and assessment methods. For asbestos and DME, significant country heterogeneity in risk estimates was observed when using expert assessment. When applying the GPJEM, the heterogeneity in risk estimates for asbestos and, to some extent, silica diminished.\ It has been previously advocated that the expert assessment approach to assign exposures based on detailed questionnaire responses provides more accurate exposure estimates than JEM-based results. However, current results demonstrated little, if any, advantage of case-by-case assessment when compared to a JEM approach.
- Добавил в систему: Заридзе Давид Георгиевич