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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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Negative Gastric Cancers: A Case-Only Analysis within the Stomach Cancer Pooling (StoP) Projectстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или ScopusДата последнего поиска статьи во внешних источниках: 4 марта 2022 г.
- Авторы: Morais S., Peleteiro B., Araújo N., Malekzadeh R., Ye W., Plymoth A., Tsugane S., Hidaka A., Hamada G.S., López-Carrillo L., Zaridze D., Maximovich D., Aragonés N., Castaño-Vinyals G., Pakseresht M., Hernández-Ramírez R.U., López-Cervantes M., Leja M., Gasenko E., Pourfarzi F., Zhang Z.F., Derakhshan M.H., Pelucchi C., Negri E., La Vecchia C., Lunet N.
- Журнал: Cancer Epidemiology Biomarkers and Prevention
- Том: 31
- Номер: 1
- Год издания: 2022
- Издательство: American Association for Cancer Research
- Местоположение издательства: United States
- Первая страница: 200
- Последняя страница: 209
- Аннотация: -negative gastric cancer (HpNGC) can be as low as 1%, when infection is assessed using more sensitive tests or considering the presence of gastric atrophy. HpNGC may share a high-risk profile contributing to the occurrence of cancer in the absence of infection. We estimated the proportion of HpNGC, using different criteria to define infection status, and compared HpNGC and positive cases regarding gastric cancer risk factors.\ infection status determined by serologic test were included. HpNGC was reclassified as positive (eight studies) when cases presented CagA markers (four studies), gastric atrophy (six studies), or advanced stage at diagnosis (three studies), and were compared with positive cases. A two-stage approach (random-effects models) was used to pool study-specific prevalence and adjusted odds ratios (OR).\ = 97), respectively. HpNGC had a family history of gastric cancer more often [OR = 2.18; 95% confidence interval (CI), 1.03-4.61] and were current smokers (OR = 2.16; 95% CI, 0.52-9.02).\ This study found a low prevalence of HpNGC, who are more likely to have a family history of gastric cancer in first-degree relatives.\ infection is present in most non-cardia gastric cancers, and suggest that HpNGC may have distinct patterns of exposure to other risk factors.
- Добавил в систему: Заридзе Давид Георгиевич