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Loss of Stability of the Blood Liquid State and Assessment of Shear-Induced Thrombosis Riskстатья Исследовательская статья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 8 декабря 2021 г.
- Авторы: Pushin D.M., Salikhova T.Yu, Biryukova L.S., Guria G.Th
- Журнал: Radiophysics and Quantum Electronics (English Translation of Izvestiya Vysshikh Uchebnykh Zavedenii, Radiofizika)
- Том: 63
- Номер: 9-10
- Год издания: 2021
- Издательство: Kluwer Academic/Plenum Publishers
- Местоположение издательства: United States
- Первая страница: 804
- Последняя страница: 825
- DOI: 10.1007/s11141-021-10097-5
- Аннотация: The loss of stability of the blood liquid state causes changes in the blood aggregation, resulting in thrombus formation. Intravascular thrombus formation is intensely studied within modern biophysics by the methods of mathematical simulation. Determining the conditions of shear-induced platelet activation has opened an opportunity for the estimation of thrombus formation risks in particular clinical settings. In this paper, a new approach is proposed to determine the risks of shear-induced thrombus formation. This approach is applicable for a wide range of objects including aorta and mechanical circulatory assist devices. The geometry of the vascular walls in numerical experiments is chosen to be isomorphic to that of the blood vessels in a human body. Promising ways to reduce the risks of thrombus formation activation in high blood flows have been found. The developed technique can be used by physicians to plan personalized strategies for antithrombotic therapy based on individual shear-induced platelet activation risks.
- Добавил в систему: Гурия Георгий Теодорович