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Trepanobiopsy as a tool for the study of the influence of presurgical treatment on the steroid receptor status of advanced breast cancerстатья
Дата последнего поиска статьи во внешних источниках: 23 сентября 2021 г.
- Авторы: Bassalyk L.S., Koposova T.L., Muravyeva N.I., Smirnova K.D., Kuzmina Z.V., Gershtein E.S., Letyagin V.P.
- Журнал: Neoplasma
- Том: 33
- Номер: 2
- Год издания: 1986
- Издательство: Vydavatel'stvo Slovenkej Akademie Vied/Veda Publishing House of the Slovak Academy of Sciences
- Местоположение издательства: Slovakia
- Первая страница: 245
- Последняя страница: 250
- Аннотация: Estrogen, progesterone and glucocorticoid receptors were determined in samples obtained by trepanobiopsy before treatment and in surgical material following chemo- or radiotherapy in 131 Stage III a, b, c breast cancer patients. The levels and distribution of the receptors in bioptates coincided with the data obtained earlier for the surgical material from patients, who didn’t receive presurgical therapy. It is concluded that breast tumor trepanobioptates may be used for the determination of tumor receptor status. Radiotherapy affected the level and frequency of occurrence of steroid hormone receptors. The degree of variations depended on the dosage of irradiation and after exposure period. After presurgical chemotherapy the percent of receptor-positive tumors increased.
- Добавил в систему: Герштейн Елена Сергеевна