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Influence of Surface Morphology of Chitosan Films Modified by Chitin Nanofibrils on Their Biological Properties / Journal: Carbohydrate Polymers, 2021, v.262, Article Number: 117917, P. 1-8статья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или ScopusДата последнего поиска статьи во внешних источниках: 10 августа 2021 г.
- Авторы: Dresvyanina E.N., Kodolova-Chukhontseva V.V., Bystrov S.G., Dobrovolskaya I.P., Vaganov G.V., Smirnova N.V., Kolbe K.A., Kamalov A.M., Ivan’kova E.M., Morganti P., Yudin V.E.
- Журнал: Carbohydrate Polymers
- Номер: 262
- Год издания: 2021
- Издательство: Pergamon Press Ltd.
- Местоположение издательства: United Kingdom
- Первая страница: 1
- Последняя страница: 8
- Номер статьи: 117917
- Аннотация: The paper is devoted to the study of influence of chitin nanofibrils on the structure, surface morphology, mechanicalproperties, and electrical conductivity of chitosan-based composite films intended for use in biomedicaltechnologies. It was demonstrated that the optimal concentration of chitin nanofibrils in the composite film is 5wt.%. For the films of this composition, we observed orientation of structural elements on film surface, enhancedmechanical properties as well as an increase in both specific conductivity and proliferative activity of skin fibroblastson film surface. These results are related to the appearance of oriented structure in nanocomposites andto self-organization of chitosan macromolecules on the surface of chitin nanofibrils. It was revealed that increasein surface energy and surface hydrophilicity did not facilitate effective adhesion, viability and proliferative activityof cells during cultivation on the surface of composite films.
- Добавил в систему: Быстров Сергей Геннадьевич