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Structural basis for cytokinin receptor signaling: an evolutionary approachстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Scopus,
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 19 июля 2013 г.
- Авторы: Steklov Mikhail Yu, Lomin Sergey N., Osolodkin Dmitry I., Romanov Georgy A.
- Журнал: Plant Cell Reports
- Том: 32
- Номер: 6
- Год издания: 2013
- Издательство: Springer Verlag
- Местоположение издательства: Germany
- Первая страница: 781
- Последняя страница: 793
- DOI: 10.1007/s00299-013-1408-3
- Аннотация: Cytokinins are ubiquitous plant hormones; their signal is perceived by sensor histidine kinases—cytokinin receptors. This review focuses on recent advances on cytokinin receptor structure, in particular sensing module and adjacent domains which play an important role in hormone recognition, signal transduction and receptor subcellular localization. Principles of cytokinin binding site organization and point mutations affecting signaling are discussed. To date, more than 100 putative cytokinin receptor genes from different plant species were revealed due to the total genome sequencing. This allowed us to employ an evolutionary and bioinformatics approaches to clarify some new aspects of receptor structure and function. Non-transmembrane areas adjacent to the ligand-binding CHASE domain were characterized in detail and new conserved protein motifs were recovered. Putative mechanisms for cytokinin-triggered receptor activation were suggested.
- Добавил в систему: Осолодкин Дмитрий Иванович