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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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Длиннолатентные слуховые вызванные потенциалы, их асимметрия и когнитивное снижение при нормальном старениитезисы доклада
- Авторы: Зеленцова Е.П., Пономарева Н.В., Малина Д.Д.
- Сборник: Материалы XVI Международной конференции по нейрокибернетике
- Том: 1
- Тезисы
- Год издания: 2012
- Место издания: Издательство ЮФУ Ростов-на-Дону
- Первая страница: 252
- Последняя страница: 254
- Аннотация: Auditory event related potentials (AERP) can be used for detecting neurophysiological changes underlying cognitive decline in normal aging. The aim of this study was to determine whether the changes of AERP parameters in frontal and parietal areas and their asymmetry are related to the results of cognitive tests in normal aging. We examined AERP in frontal and parietal areas and cognitive tests in 22 healthy subjects (age-range 19 - 84 years). All persons underwent cognitive screening. Our results showed that aging was associated with cognitive decline and the increase in the AERP P3 latency in frontal and parietal areas. Lower scores in neuropsychological tests correlated with the increase in the AERP N2 latency in parietal areas and AERPP3 latency in frontal areas. More pronounced increase in the latency in right hemisphere in comparison with the left hemisphere was related to the lower scores in the attention and memory tests. The relative decrease of the P2, N2 and N3 amplitude in parietal comparing to frontal areas correlated with cognitive decline. The results suggest that the slowing of information processing, frontoparietal redistribution of these processes and their interhemispheric asymmetry are related to cognitive decline in normal aging.
- Добавил в систему: Малина Д.Д.