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Reconsolidation of a context long-term memory in the terrestrial snail requires protein synthesisстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
- Авторы: Gainutdinova Tatiana H., Tagirova Rosa R., Ismailova Asja I., Muranova Lyudmila N., Samarova Elena I., Gainutdinov Khalil L., Balaban Pavel M.
- Журнал: Learning & memory (Cold Spring Harbor, N.Y.)
- Том: 12
- Номер: 6
- Год издания: 2005
- Первая страница: 620
- Последняя страница: 625
- DOI: 10.1101/lm.25705
- Аннотация: We investigated the influence of the protein synthesis blocker anisomycin on contextual memory in the terrestrial snail Helix. Prior to the training session, the behavioral responses in two contexts were similar. Two days after a session of electric shocks (5 d) in one context only, the context conditioning was observed as the significant difference of behavioral response amplitudes in two contexts. On the day following testing of context learning, a session of "reminding" was performed, immediately after which the snails were injected with anisomycin or vehicle. Testing of long-term context memory has shown that only anisomycin injections impaired the context conditioning. In control series, the snails were injected after the training session with anisomycin/saline without reminding, and no impairment of the long-term context memory was observed, while injection of anisomycin during the training session completely abolished the long-term memory. No effects of anisomycin on the short-term memory were observed. Surprisingly, injection of anisomycin after the reminding combined with reinforcing stimuli elicited no effect on the context memory. Differences between single-trial and multisession learning are discussed.
- Добавил в систему: Балабан Павел Милославович