Modern Methods of Stereotactic Radiosurgery and Radiotherapy for the Treatment of Cushing Diseaseстатья

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[1] Modern methods of stereotactic radiosurgery and radiotherapy for the treatment of cushing disease / A. Abdali, L. Astaf`eva, Y. Trunin et al. // Neurology India. — 2020. — Vol. 68, no. 7. — P. 129–133. Cushing's disease is caused by a pituitary tumor causing increased production of adrenocorticotropic hormone, which leads to chronic hypersecretion of cortisol through adrenal cortices. Endoscopic trans-sphenoidal adenomectomy is the first choice of treatment with greatest efficiency for the treatment of the disease. However, in the absence of remission or recurrence of hypercortisolism after neurosurgical resection (adenomectomy), as well as in cases when surgical intervention cannot be carried due to medical contraindications to surgical intervention, radiation treatment is used as an alternative or adjoining therapy. In this literature review the efficiency of different radiation techniques (the conventional and the modern techniques), as well as possible complications of modern methods of radiosurgery and radiotherapy have been looked for.Keywords: Conventional-RT, Cushing disease, cyber-knife, fractionated stereotactic radiosurgery, gamma-knife, proton-therapy. stereotactic radiosurgery, radiotherapyKey Message: The modern methods of Radiosurgery and Hypo fractionated radiosurgery allow us to achieve quicker remission in most patients with CD with minimal risk of complications. Is used as adjoining treatment to TSS or alternative treatment for variable severities of CD or as an alternative to bilateral adrenalectomy (in severe cases). [ DOI ]

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