Аннотация:Recognition memory was investigated during involuntary encoding situation.
18 healthy right-handed subjects (9 males) 18-28 y.o. participated. The experiment consists of two series. In the first series pictures of different objects were shown sequentially for 1000 ms. The subjects were instructed to classify objects as ‘animated’/‘inanimated’. The second series in which previously presented and new stimuli were shown quasi-randomly was conducted in 48 hours. The subjects had to decide if they had seen an object before. 19-channel EEG was registered. Event-related potentials were averaged during presentation of objects according to the answers. Then dipole sources were calculated using of BrainLoc 6.0 software (two-dipole dynamic model, KD 0.95).
The activation of right cingulate gyrus was revealed at latency 300-400 ms during the recognition of previously presented stimuli. Furthermore, activation was observed in right putamen (100 and 500 ms) and left hippocampus (200 ms) during the recognition of stimuli as new. We could hypothesize that there are two functional systems connected with recognition memory according these findings: the first one is responsible for recognition of previously presented stimuli and the second one supports recognition of objects as new. Right cingulate gyrus is involved in functioning of the first system, while combined work of right putamen and right hippocampus provides functioning of the second system. We suppose that hippocampus is responsible for the retrieval of information from episodic memory while putamen has a modulating effect on it.
The research was supported by the Russian Science Foundation (project@16-18-00066).