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Neurogenic constrictor response of isolated small renal arteries in rats after 2-week simulated microgravityстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 28 мая 2015 г.
- Авторы: Kalentchuk V., Tarasova O., Tsvirkoun D., Vinogradova O.
- Журнал: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology
- Том: 11
- Номер: 2
- Год издания: 2004
- Издательство: Galileo Foundation
- Местоположение издательства: El Cerrito, CA, United States
- Первая страница: P99
- Последняя страница: P100
- Аннотация: The study was aimed at investigation of the effects of 2-week tail suspension upon the constrictor responses of isolated small renal arteries in rats. 1st-2nd-order branches of renal artery were perfused with saline under the constant flow conditions. Constrictor responses to electrical stimulation of periarterial nerves, noradrenaline and serotonin were investigated. In post-suspension rats as compared to controls the response to nerve stimulation was slightly reduced during 15-Hz stimulation, but similar at smaller frequencies. Thus, simulated microgravity has no prominent effect of neurogenic responses of renal vessels, in agreement with non-changed density of periarterial adrenergic nerve plexus. Along with that, in post-suspension rats impairment of prejunctional sympathetic mechanisms might be compensated by augmented sensitivity of vascular smooth muscle to vasoconstrictors.
- Добавил в систему: Тарасова Ольга Сергеевна