Sensory conflict as a possible reason for disturbed postural stability in the children treated for cancer

Chechelnitskaia, S.; Kasatkin, V.N.; Shurupova, M.A.; Borodina, I.D.; Sarajkin, Y.V.; Karelin, A.F.; Skvorcov, D.V.; Baerbakh, A.V.; Zhuk, D.V.; Nikulin, V.A.

Авторы: Chechelnitskaia S., Kasatkin Vladimir N., Shurupova Marina A., Borodina Irina D., Sarajkin Yurij V., Karelin Aleksandr F., Skvorcov Dmitrij V., Baerbakh Aleksandra V., Zhuk Daria V., Nikulin Vladislav A.
Журнал: Cellular Therapy and Transplantation
Том: 8
Номер: 4
Год издания: 2019
Издательство: Hamburg University
Местоположение издательства: Germany
Первая страница: 68
Последняя страница: 76
DOI: 10.18620/ctt-1866-8836-2019-8-4-68-76
Аннотация: Disorders of postural resistance are widespread among the patients treated for cancer. The question of the mechanism of this phenomenon is under the study. The aim of our retrospective study was to clarify the relationship of postural instability in cancer patients with oculomotor muscle dysfunction. The study involved 291 children 5-18 years old who had cancer and were in remission state or stable clinical condition. The control group included 182 healthy children. The quality of postural balance was evaluated by stabilometric method using a computer-assisted stabilizer (Stabilan 01-2 model). The eye movements were recorded by videoculography using the Arrington eye-tracker. Regression analysis was used to assess relationships of the analyzed parameters. For explicit asymmetric distributions, we used conversion of initial values to logarithmic form and the Box-Cox transformation. The main stabilometric indicators in the position with open eyes confirmed impaired postural balance in the children who survived cancer. We have substantiated a high probability of correlation between the postural imbalance and disease factor. Improvement in stabilometric indexes with eyes closed was detected for both groups. However, this phenomenon proved to be significant and was more common among the children who survived cancer. A stable relationship was found between the postural instability and altered functioning of oculomotor muscles.
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Sensory conflict as a possible reason for disturbed postural stability in the children treated for cancerстатья

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