A comparative study on the u.v. resistance of double-stranded and single-stranded encephalomyocarditis virus RNAs: evaluation of the possible contribution of host-mediated repairстатья

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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.

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[1] Koonin E. V., Chumakov K. M., Agol V. I. A comparative study on the u.v. resistance of double-stranded and single-stranded encephalomyocarditis virus rnas: evaluation of the possible contribution of host-mediated repair // Journal of General Virology. — 1980. — Vol. 49, no. 2. — P. 437–441. To reveal previously suggested host-mediated repair of u.v.-induced lesions in dsRNA of encephalomyocarditis (EMC) virus, two sets of experiments have been carried out: (i) samples of dsRNA of EMC virus were irradiated with different doses of u.v. light and their infectivity was assayed in krebs II cells, before and after conversion of dsRNA into a ss form: (ii) samples of ssRNA of EMS virus were similarly irradiated and their infectivity was assayed before and after conversion of ssRNA into a ds form. No evidence for a significant host-mediated repair of dsRNA in this virus-cell system has been obtained.

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