|
ИСТИНА |
Войти в систему Регистрация |
Интеллектуальная Система Тематического Исследования НАукометрических данных |
||
Influence of ecdysterone on the growth of cells and synthesis of macromolecules in established cell lines of Drosophila melanogasterстатья
Информация о цитировании статьи получена из
Scopus
Дата последнего поиска статьи во внешних источниках: 4 мая 2020 г.
- Авторы: Gvozdev V.A., Kakpakov V.T., Mukhovatova L.M., Polukarova L.Y., Tarantul V.Z.
- Журнал: The Soviet journal of developmental biology
- Том: 5
- Номер: 1
- Год издания: 1975
- Издательство: Plenum
- Местоположение издательства: New York, Netherlands
- Первая страница: 29
- Последняя страница: 36
- Аннотация: Ecdysterone (beta-ecdysone) and 2-deoxy-alpha-ecdysone specifically inhibit the growth of established embryonic cells of D. melanogaster. A preparation of alpha-ecdysone is 100 times less active than ecdysterone. The action of ecdysterone is eliminated when it is removed within 24 h, but after 48 h the inhibiting influence of the hormone becomes irreversible. The diploid line, triploid and tetraploid sublines are sensitive to ecdysterone. The diploid subline with a spontaneously arisen translocation of an X-chromosome to an autosome of the third pair is substantially more resistant to ecdysterone. At 24 h after the addition of ecdysterone, there is a 2-5-fold suppression of the synthesis of total RNA; DNA synthesis is lowered to the same degree only after 48 h. The gross synthesis of proteins, measured according to the incorporation of C 14-lysine, was not suppressed even after 48 h.
- Добавил в систему: Гвоздев Владимир Алексеевич