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Quantitative techniques for extraction of blood oxygenation from multispectral optoacoustic measurementsстатья
Информация о цитировании статьи получена из
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 4 мая 2020 г.
- Авторы: Perekatova VV, Subochev PV, Kirillin M.Yu, Sergeeva EA, Kurakina DA, Orlova AG, Postnikova AS, Turchin IV
- Журнал: Laser Physics Letters
- Том: 16
- Номер: 11
- Год издания: 2019
- Издательство: Wiley - VCH Verlag GmbH & CO. KGaA
- Местоположение издательства: Germany
- Первая страница: 116201-1
- Последняя страница: 116201-12
- Аннотация: We report on the comparison of two approaches to the reconstruction of oxygen saturation (StO2) within blood vessels from multispectral optoacoustic (OA) measurements. The spatially-resolving approach is based on determination of the optical absorption coefficient µ a from OA signal amplitudes, while the calibration-free approach is based on evaluation of the effective optical attenuation coefficient µ eff derived from the in-depth OA signal decay. Both approaches were verified in phantom experiments as well as in in vitro and in vivo measurements. The results demonstrate good agreement of µ a spectra derived from OA signal amplitudes with the published data indicating this approach to be preferable for the in vivo determination of StO2. Reconstruction of µ a spectra from the in vivo measured OA signal amplitudes in a rat yields StO2 values of 0.57 ± 0.08 and 0.50 ± 0.07 for two veins of the thoracic spine. We demonstrate that for cost-effective measurements a dual-probing wavelength scheme can be employed instead of multiple wavelength probing. We found that the probing wavelength of 700 nm combined with a wavelength from the range of 850–1069 nm provides reconstructed StO2 values close to the reference ones derived from multiple wavelength measurements in the entire range of 658‒1069 nm.
- Добавил в систему: Сергеева Екатерина Александровна