|
ИСТИНА |
Войти в систему Регистрация |
Интеллектуальная Система Тематического Исследования НАукометрических данных |
||
Magnetic Nanorods for remote disruption of lipid membranes by non-heating low frequency magnetic fieldстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 24 января 2020 г.
- Авторы: Le-Deygen Irina M., Vlasova Kseniya Yu, Kutsenok Ekaterina O., Usvaliev Azizbek D., Efremova Maria V., Zhigachev Alexander O., Rudakovskaya Polina G., Golovin Dmitry Yu, Gribanovsky Sergey L., Kudryashova Elena V., Majouga Alexander G., Golovin Yury I., Kabanov Alexander V., Klyachko Natalia L.
- Журнал: Nanomedicine: Nanotechnology, Biology, and Medicine
- Том: 21
- Номер: 102065
- Год издания: 2019
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Первая страница: 1
- Последняя страница: 10
- DOI: 10.1016/j.nano.2019.102065
- Аннотация: This work presents direct evidence of disordering of liposomal membranes by magnetic nanoparticles during their exposures to non-heating alternating Extremely Low Frequency Magnetic Field (ELF MF). Changes in the lipid membrane structure were demonstrated by the Attenuated total reflection Fourier Transform Infrared and fluorescence spectroscopy. Specifically, about 50% of hydrophobic chains became highly mobile under the action of ELF MF. Magnetic field-induced increase in the membrane fluidity was accompanied by an increase in membrane permeability and release of solutes entrapped in liposomes. A physical model of this process explaining experimental data is suggested. The obtained results open new horizons for the development of systems for triggered drug release without dangerous heating and overheating of tissues.
- Добавил в систему: Клячко Наталья Львовна