Ambulatory blood pressure and arterial stiffness web-based telemonitoring may help to assess vascular health in subjects with hypertension or other conditions at risk for cardiovascular disease. First results of the VASOTENS (...) Registryстатья

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Дата последнего поиска статьи во внешних источниках: 1 августа 2019 г.

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1. Полный текст Omboni_2019_VASOTENS_Registry_01.pdf 1,3 МБ 26 июля 2019 [YAOrlova@mc.msu.ru]

[1] Ambulatory blood pressure and arterial stiffness web-based telemonitoring may help to assess vascular health in subjects with hypertension or other conditions at risk for cardiovascular disease. first results of the vasotens (...) registry / O. Stefano, P. Igor, P. Gianfranco et al. // Journal of Clinical Hypertension. — 2019. — P. 1–14. Background: Cuff-based oscillometric devices now allow combined estimation of some vascular biomarkers over the 24-hours by ambulatory blood pressure monitoring (ABPM). We implemented few years ago a Registry of such ABPM recordings with several objectives, including evaluation of long-term cardiovascular (CV) prognosis. In the present paper we present and compare the results of baseline data according to different categories of subjects’ CV risk. Methods: ABPM was performed following current guidelines by a clinically validated non-invasive oscillometric upper-arm BP monitor. Remote data collection was ensured by a certified web-based telemedicine platform. Individual readings were averaged for each ABPM recording in order to obtain 24-hour, day-and night-time, and each hour mean of brachial and aortic systolic (SBP) and diastolic blood pressure (DBP), pulse wave velocity (PWV) and augmentation index (AIx). Results were adjusted for subjects-related factors. Results: 1,200 subjects enrolled in 16 hypertension centers worldwide were included in the analysis (25% aged 65 years or older, 55% males, 48% with known hypertension, 27% dyslipidemia, 7% diabetes, 35% metabolic syndrome and 10% CV disease). Ambulatory brachial and aortic BP displayed a typical parallel circadian rhythm with decreased values during night sleep. PWV dropped and AIx rose at night. Peripheral and central BP and PWV values were increased in older subjects (SBP only) and in case of hypertension (SBP and DBP). Ambulatory BP was lower and PWV higher in females. PWV was increased and BP unchanged in case of metabolic syndrome. AIx did not show significant differences across groups. Conclusions: Preliminary results of the VASOTENS Registry suggest that ambulatory pulse wave analysis in a daily life setting may help evaluate vascular health of individuals at risk for CV disease. [ DOI ]

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