|
ИСТИНА |
Войти в систему Регистрация |
Интеллектуальная Система Тематического Исследования НАукометрических данных |
||
The effect of carbamazepine on the content of monoamines and their metabolites in the brain structures of rats with audiogenic epilepsy [Vliianie karbamazepina na soderzhanie monoaminov i ikh metabolitov v strukturakh mozga krys s audiogennoi épilepsiei.]статья
- Авторы: Kosacheva E.S., Kudrin V.S., Fedotova I.B., Semiokhina A.F., Raevskii K.S.
- Журнал: Eksperimental’naia i klinicheskaia farmakologiia
- Том: 61
- Номер: 3
- Год издания: 1998
- Первая страница: 25
- Последняя страница: 27
- Аннотация: It was shown that the content of serotonin (5-OT) and 5-oxyindoleacetic acid (5-OIAA) in the temporal cortex, hippocampus and medulla oblongata and the content of dopamine and 3,4-dihydroxyphenilacetic acid in the striatum are increased initially, while the level of norepinephrine in the striatum is reduced in Krushinskii-Molodkina rats genetically predisposed to audiogenic epilepsy in comparison with Wistar rats. Carbamazepine levelled out the changes in the 5-OT and 5-OIAA levels at the peak of the audiogenic attack in the temporal cortex and hippocampus, causing at the same time a sum increase in the content of all monoamines and their metabolites in the medulla oblongata and striatum.
- Добавил в систему: Федотова Ирина Борисовна