Аннотация:Experiments were conducted on mice of two lines - RSB and RLB. High aggression of RSB mice was not decreased after neonatal buspirone injections but increased, whereas for RLB the positive aggression decreasing was observed. It implies that the change of conditions of brain serotoninergic system formation under effect of 5-HT1A-agonist can lead to different consequences dependent on genotype peculiarities of C.N.S.