ECD and CID fragmentation of the supermetallized complexes of Substance P with K, Cs and Agстатья
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Дата последнего поиска статьи во внешних источниках: 3 октября 2016 г.
Аннотация:We report the investigation of the collision induced dissociation (CID) and electron capture dissociation (ECD) products fragmentation of the supermetallized complexes of Substance P and several monovalent metals. The supermetallization is the phenomenon of the formation of the complex ion peptide-metals in the gas phase when the peptide accepts unexpectedly large number of metals. We have obtained and investigated complexes with incorporation of up to 4 Cs, up to 5 K and up to 6 Ag atoms. The current research reveals crucial changes in the complex behavior in the cases of different metals. It was observed that in CID spectrum of complexes with Cs and K dominates the peak corresponding to the loss of metal cation while ECD gives rich fragmentation. In the case of complexes with Ag the loss of Ag+ occurs in ECD while the CID shows the good fragmentation