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[The effect of heparin and thromboplastin on the half-life of 125I-protein C in the blood flow of rats]статья
Дата последнего поиска статьи во внешних источниках: 23 января 2020 г.
- Авторы: Kogan A.E., Strukova S.M.
- Журнал: Biulleten' eksperimental'no∎ biologii i meditsiny
- Том: 111
- Номер: 2
- Год издания: 1991
- Издательство: Administrativnoia Zdaniia Minzdrava Sssr
- Местоположение издательства: Moskva, Russia (Federation)
- Первая страница: 116
- Последняя страница: 8
- Аннотация: The influence of heparin and thromboplastin on the halflife of 125I-protein C in rat blood was under investigation. It was found that t1/2 of protein C was of 2.3 h. The intravenous administration of heparin resulted in the prolongation of t1/2 to 6.5 h, that could be explained by inhibition of thrombin generation. Upon the 40-min infusion of thromboplastin the rate of 125I-protein C decay in blood enhanced. That could be explained by the generation of the endogenous thrombin and participation of thrombomodulin in the protein C activation as well as in the removal of the endogenous thrombin from blood.
- Добавил в систему: Струкова Светлана Михайловна