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[Changes in the behavior and EEG of rats administered penicillin and a physiological solution into the amygdalar basal nuclei]статья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 декабря 2013 г.
- Авторы: Pankova N.B., Kryzhanovski? G.N., Kuznetsov I.u.B, Latanov A.V.
- Журнал: Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova
- Том: 49
- Номер: 2
- Год издания: 1999
- Издательство: Izdatel'stva Nauka
- Местоположение издательства: Russian Federation
- Первая страница: 321
- Последняя страница: 330
- Аннотация: Three weeks after implantation of the electrodes for EEG recording, hyperactivation of the basal nucleus of rat’s amygdala was produced by a local injection of penicillin (0.5 mcl, 1% solution). Saline injection of the same volume served as control. The hyperactivation of the amygdala resulted in a long-lasting (at least for 3 weeks) increase in the locomotor activity against the background and deficit in exploratory behavior and rise of the level of anxiety and fear. The behavioral changes were accompanied by a long-term disruption of the hippocampal theta rhythm, appearance and slowing of the immobility-related high-voltage spindles, and increase in the EEG dominant frequency in the state of emotional tension. Saline injection led to a short-time (up to 1 week) decrease in locomotor and exploratory activity and increase in anxiety. These phenomena were accompanied by a short-time disruption of the theta rhythm and appearance of the 10-13-Hz oscillations characteristic for the state of emotional tension.
- Добавил в систему: Латанов Александр Васильевич