Аннотация:The UASB reactor (35 oC) was quite efficient for removal of bulk COD (52-74%) from simulated (on the basis of cultivation medium from the first separation process) general effluent of baker’s yeast factory (the average organic loading rates varied from 8.1 till 16 g COD/l/d). The aerobic-anoxic biofilter (19-23 oC) can be used for removal of remaining BOD and ammonia from anaerobic effluents; however, it suffered from COD-deficiency to fulfil denitrification requirements. To balance COD/N ratio, some bypass (10-11%) of anaerobically untreated general effluent should be added to the biofilter feed. The application of iron chloride coagulation for post-treatment of aerobic effluents can fulfil the discharge limits (even for colour mainly exerted by hardly biodegradable melanoidins) under iron concentrations around 200 mg/l.