The Effects of Immunization against Cholecystokinin Fragment 30–33 in the Behavior of White Ratsстатья
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Дата последнего поиска статьи во внешних источниках: 28 июня 2018 г.
Аннотация:Active immunization of white rats with cholecystokinin-4 covalently linked to the antigen carrier BSA evoked long-lasting changes in the rats' behavior, which were in the opposite direction to the anxiogenic effects of cholecystokinin-4 itself, showing that immunization had anxiolytic effects. Immunoenzyme analysis demonstrated the presence of antibodies to cholecystokinin-4 in the serum of immunized rats. These data are interesting from the point of view of correcting pathological anxiety and fear states by inverse immunoregulation