Аннотация:A complementary gas sensor and gas chromatography/mass spectrometry study was performed to investigate the chemical basis of acetone vapor sensing via semiconductor metal oxide gas sensors. The effect of additives to nanocrystalline SnO 2 -based sensor materials was analyzed. The main process that contributes to the electrical yield of this interaction and thus to the sensor response is a complete acetone oxidation to CO 2 and H 2 O. At the same time it is clearly shown that this sensor response is severely limited by the rate of desorption of the reaction products. The main contributors to this negative influence on the sensor response are heavy organic compounds with molar masses larger than that of acetone. It is also shown that their negative effect could be mitigated by the incorporation of catalytic clusters of gold on the surface of SnO 2 based sensor materials. This kind of catalyst acts either as a preventor of the formation of heavy and complex organic molecules on the sensor surface or as a combustion catalyst, which facilitates their decomposition.