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A New Approach to the Production of Bioresorbable Suture Materials with Biological Activityстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 11 апреля 2019 г.
- Авторы: Khavpachev M.A., Trofimchuk E.S., Nikonorova N.I.
- Журнал: Materials Science Forum
- Том: 935
- Год издания: 2018
- Издательство: TRANS TECH PUBLICATIONS LTD
- Местоположение издательства: LAUBISRUTISTR 24, STAFA-ZUERICH,SWITZERLAND, CH-8712
- Первая страница: 94
- Последняя страница: 99
- DOI: 10.4028/www.scientific.net/MSF.935.94
- Аннотация: The advantages of structural-mechanical modification of fibers by the mechanism of crazing for obtaining bioresorbable suture materials with biological activity are shown. Optimal conditions for realization of solvent crazing of polylactide fibers are determined as the stretching rate is not more than 75% / min and the ethanol content in the water-ethanol mixture is not less than 30-40% by weight. In this case, the value of yield stress decreases by 3-5 times, and the breaking elongation increases to 400-600%. The process of uniaxial deformation of fibers under these conditions is accompanied by the formation of a highly dispersed oriented structure with a pore diameter and fibrils of about 20-30 nm and bulk porosity up to 60% by volume. Moreover, the crazing of fibers based on polylactide under these conditions is accompanied by low-temperature crystallization, reaching a degree of crystallinity of 40%. The monofilaments based on polylactide containing biologically active additives (brilliant green, fuchsine) by the crazing mechanism are obtained. Such materials are promising for use in medicine as bioresorbable sutures with antibacterial activity.
- Добавил в систему: Хавпачев Мухамед Аликович