Properties of Oil1/Water/Oil2 Double Emulsions Containing Lipophilic Acrylic Polymerстатья
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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:Abstract—Stable oil1/water/oil2 (o1/w/o2) double emulsions (DEs) containing glyceryl monooleate as a promoter of skin permeability in internal ultradispersed phase o1 (heptane) and an acrylic polymer as a pressure sensitive adhesive in external dispersion medium o2 (ethyl acetate) are obtained. The aqueous interlayer of the DEs contains Tween 80, hydroxypropyl cellulose, and sometimes lysozyme. The phase ratio in the emulsions
is constant. The effect of polyacrylate concentration on the stability, microstructure, and rheological properties of DEs is studied. Factors of DE stability, with the viscoelastic properties of the external dispersion medium being of the most importance, are analyzed. The DEs are used to produce ultradisperse films, which exhibit longterm release of lysozyme at a constant rate with its enzymatic activity retained preserved. The diffusion coefficient of the protein in the polymer matrix is determined.