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Интеллектуальная Система Тематического Исследования НАукометрических данных |
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Calcium Orthophosphate (CaPO4) Scaffolds for Bone Tissue Engineering Applicationsстатья
- Автор: Dorozhkin Sergey V.
- Журнал: Journal of Biotechnology and Biomedical Science
- Том: 1
- Номер: 3
- Год издания: 2018
- Первая страница: 25
- Последняя страница: 93
- DOI: 10.14302/issn.2576-6694.jbbs-18-2143
- Аннотация: The chemical and structural similarities of calcium orthophosphates (abbreviated as CaPO4) to the mineral composition of natural bones and teeth have made them a good candidate for bone tissue engineering applications. Nowadays, a variety of natural or synthetic CaPO4-based biomaterials is produced and has been extensively used for dental and orthopedic applications. Despite their inherent brittleness, CaPO4 materials possess several appealing characteristics as scaffold materials. Namely, their biocompatibility and variable stoichiometry, thus surface charge density, functionality and dissolution properties, make them suitable for both drug and growth factor delivery. Therefore, CaPO4, especially hydroxyapatite (HA) and tricalcium phosphates (TCPs), have attracted a significant interest in simultaneous use as bone grafts and drug delivery vehicles.
- Добавил в систему: Дорожкин Сергей Вениаминович